Steve Jobs Stanford Commencement Speech 2005

3 key points for me:

1-   you can't connect the dots looking forward;
you can only connect them looking backward. So you have to trust that the dots
will somehow connect in your future. You have to trust in something — your gut,
destiny, life, karma, whatever.

2-    - Your work is going to fill a large part of
your life, and the only way to be truly satisfied is to do what you believe is
great work. And the only way to do great work is to love what you do. If you
haven't found it yet, keep looking. Don't settle.

3-     - Remembering that you are going to die is the
best way I know to avoid the trap of thinking you have something to lose. You
are already naked. There is no reason not to follow your heart.